| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Original Article
Volume 6, Number 5, October 2015, pages 437-440
FCGRs Polymorphisms and Response to Trastuzumab in Patients With HER2-Positive Breast Cancer: Far From Predictive Value?
Table
| pCR | P-value | ||
|---|---|---|---|
| Yes (N = 12) | No (N = 14) | ||
| pCR: pathological clinical response. | |||
| FCGR2A His131Arg (A>G) | |||
| AA | 3 (25.0) | 7 (50.0) | |
| AG | 3 (25.0) | 7 (50.0) | |
| GG | 6 (50.0) | 0 (0.0) | 0.012 |
| FCGR3A Val212Phe (T>G) | |||
| TT | 3 (25.0) | 4 (28.5) | |
| TG | 8 (66.7) | 7 (50.0) | |
| GG | 1 (8.3) | 3 (21.5) | 0.590 |