World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
Journal website http://www.wjon.org |
Original Article
Volume 8, Number 3, June 2017, pages 76-80
Uterine Smooth Muscle Tumor of Uncertain Malignant Potential: Clinicopathologic-Sonographic Characteristics, Follow-Up and Recurrence
Tables
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | |
---|---|---|---|---|---|---|
MM: meno-metrorrhagia. Echogenicity: anechoic, hypoechoic, isoechoic, hyperechoic, mixed (hypo-hyperechoic). Appearence: homogenous, heterogenous. +: present, -: absent. NR: not to be reached. | ||||||
Age | 48 | 44 | 40 | 43 | 52 | 24 |
Gravida | 12 | 8 | 2 | 4 | 7 | 0 |
Parity | 5 | 6 | 2 | 4 | 4 | 0 |
Menopausal state | Post | Pre | Pre | Pre | Pre | Pre |
Complaint | MM | MM | MM | MM | MM | MM and pelvic pain |
Sonographic findings | ||||||
Number of tumor/myoma | 5 | 1 | 1 | 1 | 1 | 2 |
Margins of the tumor | Ill-defined | Well-defined | Well-defined | Well-defined | Well-defined | Well-defined |
Echogenicity | Mixed | Mixed | Hyperechoic | Hyperechoic | Hyperechoic | Hyperechoic |
Appearance | Heterogenous | Heterogenous | Heterogenous | Heterogenous | Heterogenous | Heterogenous |
Cystic form | + | + | - | - | - | - |
Calcification | - | + | + | - | - | + |
Acoustic shadowing | + | - | - | + | + | + |
Free fluid | - | - | - | - | - | - |
Pathology | ||||||
Procedure | TAH + BSO | TAH + BSO | Myomectomy | TAH + BSO | TAH + BSO | Myomectomy |
Tumor diameter (cm) | 3.5 | 8 | 7 | 20 | 10 | 8 |
Localization | Intramural | Submucous | Intramural | Intramural | Intramural | Intramural |
Number of mitosis (n/10 HPF) | 4 | 17 | 8 | 5 | 8 | 6 |
Atypia | Mild | Moderate | Moderate | Moderate | Mild | Moderate |
Necrosis | + | + | - | - | - | - |
Follow-up (months) | 120 | 119 | NR | 38 | 29 | 11 |
Recurrence | - | - | NR | - | - | + |
Age, mean ± SD (min. - max.) | 41.8 ± 9.7 (24 - 52) |
Gravida, mean ± SD (min. - max.) | 5.5 ± 4.4 (0 - 12) |
Parity, mean ± SD (min. - max.) | 3.5 ± 2.2 (0 - 6) |
Menapausal state, n (%) | |
Postmenapause | 1 (16.7) |
Premenapause | 5 (83.3) |
Complaint, n (%) | |
Meno-metrorrhagia | 6 (100) |
Sonography | |
Number of tumor/myoma, mean ± SD (min. - max.) | 1.8 ± 1.6 (1 - 5) |
Margins of the tumor, n (%) | |
Ill-defined | 1 (16.7) |
Well-defined | 5 (83.3) |
Tumor echogenicity, n (%) | |
Hyperechoic | 4 (66.7) |
Mixed | 2 (33.3) |
Tumor heterogenicity, n (%) | |
Heterogenous | 6 (100) |
Cystic appearance, n (%) | |
+ | 2 (33.3) |
- | 4 (66.7) |
Calcification n (%) | |
+ | 3 (50.0) |
- | 3 (50.0) |
Acoustic shadowing, n (%) | |
+ | 4 (66.7) |
- | 2 (33.3) |
Free fluid, n (%) | 0 |
Pathology | |
Procedure, n (%) | |
Myomectomy | 2 (33.3) |
TAH + BSO | 4 (66.7) |
Tumor diameter (cm), mean ± SD (min. - max.) | 9.4 ± 5.6 (3.5 - 20) |
Localization, n (%) | |
Intramural | 5 (83.3) |
Submucous | 1 (16.7) |
Mitosis count (n/10 HPF), mean ± SD (min. - max.) | 8.0 ± 4.7 (4 - 17) |
Atypia, n (%) | |
Mild | 2 (33.3) |
Moderate | 4 (66.7) |
Necrosis, n (%) | |
+ | 2 (33.3) |
- | 4 (66.7) |
Final situation n (%) | |
Recurrence | 1 (20) |
Disease-free | 4 (80) |
NR | 1 |
Follow-up (months), mean ± SD (min. - max.) | 63.4 ± 52.1 (11 - 120) |