World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website

Case Report

Volume 9, Number 1, February 2018, pages 29-34

Atypical Presentation of Acute Myeloid Leukemia


Figure 1.
Figure 1. Electrocardiogram (ECG) showing sinus tachycardia, rate 103 beats per minute, ST segment elevation in leads I, II, aVL and V5 with PR elevation and ST depression in aVR.
Figure 2.
Figure 2. Peripheral smear showing increase in myeloid precursors with blasts.
Figure 3.
Figure 3. (a) Low power bone marrow (H&E, × 40) demonstrating a packed marrow. (b) High power bone marrow (H&E, × 200) showing cellular infiltrates with high nuclear/cytoplasmic ratio and prominent nucleoli consistent with myeloblasts. (c) High power bone marrow aspirate with Giemsa-Wright stain (× 600) showing myeloblasts.
Figure 4.
Figure 4. (a) Flow cytometry of the ungated scattergram plot of the marrow aspirate showing a high proportion of events in the dim CD45/low side scatter region (black dots). (b) Blast gate showing expression for CD117 and partial expression for CD34 consistent with blasts.
Figure 5.
Figure 5. Flow cytometry acute myeloid and lymphoid analysis: marrow aspirate with immunophenotypic profile consistent with involvement by AML (non-M3 phenotype).


Table 1. Workup for Myopericarditis
Human immunodeficiency virus (HIV)Not detected
Hepatitis ANot detected
Hepatitis B surface antigenNot detected
Hepatitis C antibodyNot detected
CytomegalovirusNot detected
Coxsackie type A and B antibodyNot detected
Influenza A and BNot detected
Parainfluenza 1-4Not detected
AdenovirusNot detected
EnterovirusNot detected
Mycoplasma pneumoniaNot detected
Antinuclear antibody (ANA)Negative
Antineutrophilic cytoplasmic antibody (ANCA)Negative


Table 2. Meningitis Panel in Cerebrospinal Fluid
Listeria monocytogenesNot detected
Neisseria meningitidisNot detected
EnterovirusNot detected
Herpes simplex virus 1 and 2Not detected
Escherichia coli K1Not detected
Hemophilus influenzaNot detected
CytomegalovirusNot detected
Streptococcus agalactiaeNot detected
Human herpesvirus 6Not detected
Human parechovirusNot detected
Varicella zoster virusNot detected
Cryptococcus neoformansNot detected