World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Review

Volume 10, Number 1, February 2019, pages 1-9

Haploidentical Stem Cell Transplantation With Post-Transplantation Cyclophosphamide for Aggressive Lymphomas: How Far Have We Come and Where Are We Going?

Table

Table 1. : Outcomes From Multiple Retrospective Studies on NHL and HL Patients Receiving Haplo-HSCT and PTCy for GvHD Prophylaxis
 
AuthorNOSPFS/EFSTRM/NRMRelapseaGvHDcGvHD
Author: last name of the first author and year of publication in a chronological order; N: the total number of haplo patients in the study; OS: overall survival at time point; PFS: progression-free survival/event-free survival at time point; TRM/NRM: transplant-related mortality/non-relapse mortality at time point; relapse: percentage of patients having relapse at time point; aGvHD: acute graft-versus-host disease, percentage of patients having grades II-IV disease at 100 days post-transplant; cGvHD: chronic graft-versus-host disease, combined limited and extensive.
Burroughs 2008 [24]2458% at 2 years51% at 2 years9% at 2 years40% at 2 years43%35% at 2 years
Raiola 2014 [37]2677% at 3 years63% at 3 years4% at 2 years31% at 2 years24%8% at 2 years
Castagna 2014 [42]4971% at 2 years63% at 2 years16.3% at 2 years18.7% at 2 years25.6%5.2% at 2 years
Dietrich 2016 [45]5956% at 2 years50% at 2 years23% at 2 years27% at 2 yearsN/AN/A
Gayoso 2016 [38]4358% at 2 years48% at 2 years21% at 1 year24% at 2 years39%19% at 2 years
Ghosh 2016 [44]18061% at 3 years48% at 3 years15% at 3 years37% at 3 years27%12% at 1 year
Kanate 2016 [43]18560% at 3 years47% at 3 years11% at 1 year36% at 3 years8%13% at 1 year
Lacerda 2017 [40]2466% at 2 years54% at 2 years26% at 2 years19% at 2 years17%24% at 2 years
Castagna 2017 [41]6263% at 3 years59% at 3 years20% at 1 year21% at 3 year23%16% at 1 year
Gauthier 2017 [35]3475% at 3 years66% at 3 years9% at 3 years25% at 3 years28%15% at 2 years
Martinez 2017 [36]9867% at 2 years43% at 2 years17% at 1 year39% at 2 years33%26% at 1 year
Mariotti
2018 [34]		6456% at 3 years60% at 3 years26% at 1 year13% at 3 years23%3% at 2 years
Marani 2018 [39]4175.6% at 3 years43.9% at 3 years8% at 3 years55.4% at 3 years20.7%11.8% at 3 years