World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Case Report

Volume 10, Number 6, December 2019, pages 231-236

Hypercalcemia in T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: An Unusual Presentation of a Rare Disease and Literature Review

Figures

Figure 1.
Figure 1. Bone marrow smears demonstrating T-cell/histiocyte rich large B-cell lymphoma. (a) Low-power view. (b) High-power view. (c) PAX8 immunostain. (d) CD3 immunostain. CD: cluster of differentiation. BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; WBC: white blood cell; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin.
Figure 2.
Figure 2. Torso positron emission tomography/computed tomography scan demonstrates diffuse fluorodeoxyglucose (FDG) uptake and a 3.98-cm splenic mass.

Table

Table 1. Summary of Laboratory Results
 
ResultReference range
Complete metabolic panel
  Sodium (mmol/L)138136 - 145
  Potassium (mmol/L)4.13.5 - 5.2
  Chloride (mmol/L)9696 - 110
  Bicarbonate (mmol/L)2924 - 31
  Calcium (mg/dL)16.18.5 - 10.5
  Magnesium (mg/dL)1.91.3 - 2.5
  Phosphorous (mg/dL)5.82.5 - 4.6
  BUN (mg/dL)675.0 - 25
  Creatinine (mg/dL)3.250.61 - 1.24
  eGFR (mL/min)19> 60
  Intact parathyroid hormone (pg/mL)6.815 - 65
  PTH-related peptide(pmol/L)3.70.0 - 2.3
  25-hydroxyvitamin D (pg/mL)16819.9 - 79.3
  β2-microglobulin (mg/L)9.81.1 - 2.4
Complete blood count
  WBC (×103/µL)4.34.5 - 11.0
  Hemoglobin (g/dL)11.412.0 - 17.5
  Hematocrit (%)34.036.0-53.0
  MCV (fL)84.080.0 - 100
  MCH (pg)28.125.0 - 35.0
  Platelet count (×103/µL)206140 - 450
Iron panel
  Iron (µg/dL)7845 - 180
  Iron binding (µg/dL)265260 - 480
  Ferritin (ng/mL)681.524 - 336
  Transferrin ((mg/dL))189215 - 365
  Transferrin % saturation (%)29.515-50