World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
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Case Report

Volume 13, Number 1, February 2022, pages 38-47

Non-GCB Diffuse Large B-Cell Lymphoma With an Atypical Disease Course: A Case Report and Clinical Exome Analysis

Figures

Figure 1.
Figure 1. PET/CT results showing disease progression. (a) Before the start of therapy. (b) After the end of therapy. (c) Following disease relapse. PET/CT: positron emission tomography combined with computed tomography.
Figure 2.
Figure 2. Results of cytogenetic examination of the cervical lymph node biopsy during disease onset and relapse. (a) Karyotype before treatment. (b) Karyotype after treatment. (c) Three main cell subclones after treatment and their karyotypes. c1: 48, X,-Y,+X,der(3),der(5)t(1;5)(q23q15), del(6)(q22),+7,der(11),+14,add(14)(q32), add(17(p13), +18,add(18)(q23),-22,add(22)(p11),+mar[7]48; c2: sdl,inv(p21q22)[4]/47,idem,sdl,-15[2]/47; c3: X,-Y,+X,der(3),del(5)(q15-21),+13,+14,add(14)(q32),+18,der(19)dic(7;19) (7qter→p11::19pter→19qter)×2,add(21)(p11),-22,add(22)(p11)[5]/46,XY[6]. der: derivative chromosome; del: deletion; add: additional; +mar: marker chromosome; sdl: sidelines; inv: inversion.
Figure 3.
Figure 3. FISH of the 17p13 deletion in cervical lymph node biopsy following disease relapse. FISH: fluorescence in situ hybridization.