World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://www.wjon.org

Review

Volume 13, Number 6, December 2022, pages 337-342

Primary Angiosarcoma of the Spleen: An Aggressive Neoplasm

Tables

Table 1. The Clinical Presentation for Patients With Splenic Angiosarcoma
 
SymptomPrevalence
Abdominal pain67-83%
Weight loss10-40%
Fatigue5-39%
Hemodynamic instability21%
Fever10%
Chest pain10%
Hemoptysis, shortness of breath, appetite loss, hematemesisLess than 1%

 

Table 2. Reported Cases of Spontaneous Spleen Rupture Due to Primary Angiosarcoma
 
CaseGenderAge (years)Clinical presentationManagementOverall survival following diagnosis
M: male. F: female. N/A: not available.
Stutz et al, 2007 [15]F45Abdominal pain and hemodynamic instabilitySplenectomy + adjuvant chemotherapy4 months
Koutelidakis et al, 2007 [16]F79NonspecificSplenectomyN/A
Manouras et al, 2008 [17]F17Abdominal pain and hemodynamic instabilitySplenectomyDisease free at 16 months’ follow-up
Miyata et al, 1993 [18]F45Abdominal painSplenectomy and adjuvant chemotherapy7 months
Mayir et al, 2007 [19]M57Abdominal pain and hemodynamic instabilitySplenectomy1 day
Raffel et al, 2010 [20]F64Abdominal painSplenectomy and adjuvant chemotherapy4 months
Simansky et al, 1986 [21]M76Abdominal pain and hemodynamic instabilitySplenectomy6 weeks
Maier et al, 2004 [22]F37Abdominal painSplenectomy and adjuvant chemotherapy6 months
Villedieu et al, 2000 [23]M53Abdominal pain and hemodynamic instabilitySplenectomy7 months
Linan-Padilla et al, 2008 [24]F35Abdominal pain and hemodynamic instabilitySplenectomy4 days
Sivelli et al, 2005 [25]F80Hemodynamic instabilitySplenectomyN/A
Winde et al, 1991 [26]FMiddle ageN/ASplenectomyN/A
Badiani et al, 2013 [27]M30Abdominal pain and hemodynamic instabilitySplenectomy0 days
Abdallah et al, 2016 [28]M55Abdominal pain and hemodynamic instabilitySplenectomy and adjuvant chemotherapyN/A
Ozcan et al, 2018 [29]F65Abdominal pain and distensionSplenectomy and adjuvant chemotherapyN/A
Teco-Cortes et al, 2021 [30]M49Abdominal painSplenectomyN/A
Bilski et al, 2018 [31]M42Abdominal pain and hemodynamic instabilitySplenectomy and adjuvant chemo-radiotherapy23 months
Xu et al, 2015 [32]F77Abdominal painSplenectomy2 weeks
Duan et al, 2013 [33]M65Abdominal pain and hemodynamic instabilitySplenectomyN/A