World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://www.wjon.org

Original Article

Volume 14, Number 1, February 2023, pages 94-100

Nephrolithiasis-Associated Renal Cell Carcinoma in Patients Who Underwent Nephrectomy: A Single-Center Experience

Figures

Figure 1.
Figure 1. Baseline characteristics of nephrolithiasis patients. (a) Comorbidities: UTI (yes: 26 (32.5%), no: 54 (67.5%)), family history of cancer (yes: 29 (36.3%), no: 51 (63.7%)), hypertension (yes: 62 (77.5%), no: 18 (22.5%)), NSAID consumption (yes: 15 (18.7%), no: 59 (81.3%)), alcohol consumption (yes: 34 (42.5%), no: 46 (57.5%)), and smoking (yes: 53 (66.3%), no: 27 (33.7%)). (b) Age (> 55 years old: 36 (40%), < 55 years old: 48 (60%); mean ± SD: 48.77 ± 7.23). NSAID: nonsteroidal anti-inflammatory drug; SD: standard deviation; UTI: urinary tract infection.
Figure 2.
Figure 2. Renal cancer histopathology characteristics which consist of squamous cell carcinoma (9 (50%)), papillary RCC (5 (27.8%)), clear cell RCC (2 (11.1%)), and collecting duct RCC (2 (11.1%)). RCC: renal cell carcinoma.
Figure 3.
Figure 3. The result of Cox’s proportional hazard regression model when comparing the cancer family history and hypertension with the possibility of causing renal cancer.

Table

Table 1. Adjusted Regression Models of the Cohort Study for the Main Outcomes
 
VariableUnivariableMultivariable
CI: confidence interval.
Hypertension2.56 (95% CI 1.075 - 6.106)1.12 (95% CI 0.95 - 1.5)
Smoking status1.54 (95% CI 1.42 - 1.68)1.03 (95% CI 0.96 - 1.1)
Family history of cancer4.5 (95% CI 2.17 - 19.8)1.39 (95% CI 1.05 - 1.84)
Urinary tract infection2.85 (95% CI 1.37 - 5.92)1.12 (95% CI 1.03 - 1.34)