World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website https://www.wjon.org

Short Communication

Volume 15, Number 1, February 2024, pages 136-142


Clinical Outcomes of Curative Intent Radiotherapy by Helical Tomotherapy for Laryngeal Squamous Cell Carcinoma: A Retrospective Analysis in a Tertiary Referral Center

Figures

Figure 1.
Figure 1. Treatment plan of helical tomotherapy: the primary and positive lymph node covered by a dose of 70 Gy. The prophylactic lymph node levels of the ipsilateral side of the lymph node-positive side (right side) are covered by 59.4 Gy. The contralateral side of the positive lymph node (left side) is covered by 54 Gy.
Figure 2.
Figure 2. Kaplan-Meier curves for overall survival (a), disease-free survival (b), local control (c), and laryngeal preservation (d) rates in all patients.

Tables

Table 1. Patient Characteristics of the Present Cohort
 
VariablesN (%)
Age, median (range)69 (41 - 84)
Sex
  Male37 (82%)
  Female8 (18%)
Karnofsky performance status
  1001 (2%)
  9036 (80%)
  808 (18%)
Tumor location
  Supraglottic28 (62%)
  Glottic14 (31%)
  Subglottic3 (7%)
Clinical T stage
  19 (20%)
  219 (42%)
  316 (36%)
  41 (2%)
Clinical N stage
  034 (76%)
  15 (11%)
  25 (11%)
  31 (2%)

 

Table 2. Combination Therapy With Curative Intent Radiotherapy, Stratified by Clinical Stage
 
VariablesN (%)
CCRT: concurrent chemoradiotherapy; ND: neck dissection; IDC: induction chemotherapy.
I
  RT alone9 (100%)
II
  RT alone13 (93%)
  CCRT1 (7%)
III
  CCRT11 (69%)
  IDC and RT alone4 (25%)
  ND and CCRT1 (6%)
IV
  RT alone1 (17%)
  CCRT3 (50%)
  IDC, ND, and CCRT2 (33%)