World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
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Case Report

Volume 15, Number 1, February 2024, pages 143-148

Significance of Beta Human Chorionic Gonadotropin in Predicting Disease Progression in Uterine Leiomyosarcoma

Figures

Figure 1.
Figure 1. Images from the leiomyosarcoma. (a) There is proliferation of spindle cells with marked pleomorphism and necrosis at upper right corner (arrow). (b) The tumor cells are strongly diffusely positive for desmin (arrow). (c) Positive cytoplasmic staining for smooth muscle actin (arrow).
Figure 2.
Figure 2. First disease progression shown on CT scan with contrast, manifested with multiple bilateral pulmonary nodules and two prominent right hilar lymph nodes, with multiple scattered destructive lytic bony lesions (arrows) (August 12, 2020) (a: coronal, bone window; b, c: axial, lung window). CT: computed tomography.
Figure 3.
Figure 3. PET/CT scan showing widespread metastatic disease (arrows) (September 10, 2020). Beta-hCG level was within normal levels. Beta-hCG: beta human chorionic gonadotropin; CT: computed tomography; PET: positron emission tomography.
Figure 4.
Figure 4. CT scan showing disease progression (February 9, 2023): enlarging extraosseous soft tissue component associated with destructive bony lesion involving the right second rib and left acetabulum, enlarging bilateral pulmonary lesions, and moderate right-sided pleural effusion with new right pleural nodular thickening, suspicious for pleural carcinomatosis (arrows). Beta-hCG level was elevated (8.43 mIU/mL). Beta-hCG: beta human chorionic gonadotropin; CT: computed tomography.