World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Case Report

Volume 2, Number 1, February 2011, pages 37-40

Hepatocellular Carcinoma and High Grade Neuroendocrine Carcinoma: A Case Report and Review of the Literature

Figures

Figure 1.
Figure 1. CT scan of liver showing a 4 cm mass in the left lobe with areas of necrosis.
Figure 2.
Figure 2. Initial liver biopsy showing a necrotic poorly differentiated carcinoma (hematoxylin and eosin, × 200).
Figure 3.
Figure 3. (a) Sharp demarcation of the both components of the moderately differentiated hepatocellular carcinoma and the neuroendocrine carcinoma with the latter showing rosettes (hematoxylin and eosin, × 100). (b) Hepatocellular carcinoma (hematoxylin and eosin, × 200).
Figure 4.
Figure 4. (a) Borderline area between both tumors showing immunoreactivity for Hep Par1 in the hepatocellular carcinoma, whereas it is negative in the neuroendocrine tumor (immunoperoxidase, × 100). (b) Neuroendocrine carcinoma showing immunoreactivity for chromogranin (immunoperoxidase, × 100).