World J Oncol

World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access

Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc

Journal website http://www.wjon.org

Original Article

Volume 2, Number 2, April 2011, pages 70-75

Quality of Life in Patients Treated with Palliative Radiotherapy for Advanced Lung Cancer and Lung Metastases

**Table 1.** Patients Demographics (N = 31)
Age (years)
n	31
Mean ± SD	68 ± 11
Inter-quartiles	58 - 77
Median (range)	69 (38 - 85)
Karnofsky Performance Scale
n	31
Mean ± SD	67 ± 16
Inter-quartiles	60 - 80
Median (range)	70 (30 - 90)
Palliative Performance Scale
n	30
Mean ± SD	65 ± 17
Inter-quartiles	60 - 80
Median (range)	70 (30 - 90)
Gender
Male	19	(61%)
Female	12	(39%)
Primary Cancer Site
Lung	25	(80%)
GI-Colon	2	(6%)
GI-Rectum	1	(3%)
Breast	1	(3%)
Prostate	1	(3.23%)
Renal Cell	1	(3%)

Table 1. Patients Demographics (N = 31)

Age (years)

Mean ± SD

68 ± 11

Inter-quartiles

58 - 77

Median (range)

69 (38 - 85)

Karnofsky Performance Scale

Mean ± SD

67 ± 16

Inter-quartiles

60 - 80

Median (range)

70 (30 - 90)

Palliative Performance Scale

Mean ± SD

65 ± 17

Inter-quartiles

60 - 80

Median (range)

70 (30 - 90)

Gender

Male

(61%)

Female

(39%)

Primary Cancer Site

Lung

(80%)

GI-Colon

(6%)

GI-Rectum

(3%)

Breast

(3%)

Prostate

(3.23%)

Renal Cell

(3%)

**Table 2.** QLQ-C15-PAL Mean Score Value for Each Symptom Item at Baseline and Follow-up
Symptom Scales/Items	Data Collection Period in Weeks
QLQ-C15-PAL scores were compared between baseline and at each follow-up visit. Scores that show significant differences at the indicated follow-up period are bolded. Significant differences were calculated using Wilcoxon Signed Rank.
Pain	45.16	30.95	26.19	31.11	19.44	25.93
Dyspnea	45.56	42.86	30.95	48.89	33.33	40.74
Insomnia	39.78	40.48	28.57	17.78	11.11	14.81
Appetite Loss	41.11	38.1	23.81	31.11	33.33	59.26
Constipation	30	28.57	21.43	24.44	16.67	40.74
Overall Quality of Life	51.67	54.76	50	56.67	52.78	55.56
Physical Functioning	57.7	59.05	67.69	57.33	57.78	52.5
Fatigue	49.46	41.88	47.62	50.37	53.54	50.62
Nausea/Vomiting	12.9	15.48	11.9	8.89	15.28	12.96
Emotional Functioning	74.14	75.6	85.12	82.22	75	64.81

Table 2. QLQ-C15-PAL Mean Score Value for Each Symptom Item at Baseline and Follow-up

Symptom Scales/Items

Data Collection Period in Weeks

QLQ-C15-PAL scores were compared between baseline and at each follow-up visit. Scores that show significant differences at the indicated follow-up period are bolded. Significant differences were calculated using Wilcoxon Signed Rank.

Pain

45.16

30.95

26.19

31.11

19.44

25.93

Dyspnea

45.56

42.86

30.95

48.89

33.33

40.74

Insomnia

39.78

40.48

28.57

17.78

11.11

14.81

Appetite Loss

41.11

38.1

23.81

31.11

33.33

59.26

Constipation

28.57

21.43

24.44

16.67

40.74

Overall Quality of Life

51.67

54.76

56.67

52.78

55.56

Physical Functioning

57.7

59.05

67.69

57.33

57.78

52.5

Fatigue

49.46

41.88

47.62

50.37

53.54

50.62

Nausea/Vomiting

12.9

15.48

11.9

8.89

15.28

12.96

Emotional Functioning

74.14

75.6

85.12

82.22

64.81

**Table 3.** QLQ-LC13 Mean Score Values for Each Symptom Item at Baseline and Follow-up
Symptom Scales/Items	Data Collection Period in Weeks
QLQ-LC13 scores were compared between baseline and at each follow-up visit. Scores with a significant difference at the indicated follow-up period are bolded. Significant differences were calculated using Wilcoxon Signed Rank.
Coughing	49.46	42.86	45.24	42.22	36.11	25.93
Hemoptysis	16.13	16.67	5.13	4.44	8.33	11.11
Sore Mouth	6.45	7.69	4.76	6.67	8.33	7.41
Dysphagia	16.13	19.05	9.52	15.56	5.56	3.7
Peripheral Neuropathy	18.89	26.19	0	17.78	5.56	11.11
Alopecia	8.89	0	7.69	28.89	30.3	37.5
Pain in Chest	27.96	30.95	26.19	15.56	19.44	22.22
Pain in Arm	22.58	16.67	9.52	24.44	5.56	18.52
Pain Other	39.78	25.64	12.82	26.67	30.56	44.44
Dyspnea	30.95	33.33	16.67	30.56	26.39	36.51
Dsypnea When Rested	2.33	1.5	2.25	2	1.33	2.5
Dyspnea When Walked	2.33	2	2.75	2	1.67	3

Table 3. QLQ-LC13 Mean Score Values for Each Symptom Item at Baseline and Follow-up

Symptom Scales/Items

Data Collection Period in Weeks

QLQ-LC13 scores were compared between baseline and at each follow-up visit. Scores with a significant difference at the indicated follow-up period are bolded. Significant differences were calculated using Wilcoxon Signed Rank.

Coughing

49.46

42.86

45.24

42.22

36.11

25.93

Hemoptysis

16.13

16.67

5.13

4.44

8.33

11.11

Sore Mouth

6.45

7.69

4.76

6.67

8.33

7.41

Dysphagia

16.13

19.05

9.52

15.56

5.56

3.7

Peripheral Neuropathy

18.89

26.19

17.78

5.56

11.11

Alopecia

8.89

7.69

28.89

30.3

37.5

Pain in Chest

27.96

30.95

26.19

15.56

19.44

22.22

Pain in Arm

22.58

16.67

9.52

24.44

5.56

18.52

Pain Other

39.78

25.64

12.82

26.67

30.56

44.44

Dyspnea

30.95

33.33

16.67

30.56

26.39

36.51

Dsypnea When Rested

2.33

1.5

2.25

1.33

2.5

Dyspnea When Walked

2.33

2.75

1.67