Figure 1. Biochemical parameters within the last 24 hours prior to death. K: potassium (mmol/dL); Ca: calcium (mg/dL); phos: phosphorrus (mg/dL); UA: uric acid (mg/dL); HD: hemodialysis.
| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Case Report
Volume 2, Number 4, August 2011, pages 204-207
Spontaneous Tumor Lysis Syndrome in Metastatic Melanoma
Figure
Table
| Reference | Age, sex | Primary site | Metastatic lesions | Trigger | Onset of TLS | Hemodialysis | Outcomes |
|---|---|---|---|---|---|---|---|
| TNF- α, tumor necrosis factor; IL-2, interleukin-2; IFN-α, interferon-α; NS, not stated. | |||||||
| 2 | 76, M | NS | Liver, lung, spleen, pelvis, lymph nodes | IFN-α, anti-GD3 ganglioside monoclonal antibody | 8 h | Not required | Died |
| 3 | 61, M | Abdomen | Liver, lung, axillary lymph node | IL-2, IFN-α, cisplatin, dacarbazine, vinblastine | 24 h | Not required | Died |
| 4 | 41, M | NS | Liver, GI tract | TNF-α, cisplatin, dacarbazine | 2 days | Initiated, but discontinued at patient’s own request in a week | NS |
| 5 | 56, F | Shoulder | Liver, lung, bone | Hydrocortisone | 7 h | Not required | Died |
| 6 | 36, F | Back | Liver, lung | IL-2, IFN-α, cisplatin, dacarbazine, vinblastine | 3 days | Initiated with improvement of renal dysfunction | Died |
| 7 | 62, M | Choroid | Liver | Transcatheter arterial infusion of cisplatin and embolization | 24 h | Initiated with improvement of renal dysfunction | Died |
| 8 | 42, M | NS | Liver, spleen, bone, Abdominal lymph nodes | Corticosteroid | 2 days | NS | Died |
| This case | 46, M | Abdomen wall | Liver, spleen, lymph node | No | Spontaneous | Required | Died |