| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Original Article
Volume 2, Number 4, August 2011, pages 175-180
Sarcomatoid Urothelial Carcinoma: A Single Cancer Center Experience
Figures


Tables
| Characteristics | UC (N = 319) (%) | Sarcomatoid (N = 14) (%) | P-value |
|---|---|---|---|
| CDS: Cancer Directed Surgery; UC: urothelial carcinoma | |||
| Age | |||
| Median (Range) | 71 (32 - 92) | 63 (45 - 93) | |
| Gender | |||
| Male | 243 (76.2) | 12 (85.7) | 0.53 |
| Female | 76 (23.8) | 2 (14.3) | |
| Race | |||
| White | 301 (94.0) | 14 (100.0) | 0.45 |
| Black | 18 (6.0) | 0 (0.0) | |
| Grade | |||
| High Grade | 182 (57.1) | 14 (100.0) | < 0.01 |
| Low Grade | 123 (38.6) | 0 (0.0) | |
| Not Specified | 14 (4.3) | 0 (0.0) | |
| AJCC Stage | |||
| < T2 | 182 (57.1) | 2 (14.3) | < 0.01 |
| ≥ T2 | 135 (42.3) | 12 (85.7) | |
| TX | 2 (0.06) | 0 (0.0) | |
| Year of Diagnosis | |||
| 2000-2005 | 112 (35.1) | 8 (57.1) | 0.09 |
| 2006-2011 | 207 (64.9) | 6 (42.9) | |
| CDS | |||
| Cystectomy | 85 (26.6) | 10 (71.4) | < 0.01 |
| TURBT alone | 222 (69.6) | 4 (28.6) | |
| None | 12 (3.8) | 0 (0.0) | |
| Case | Stage | Tumor Size (cm) | Hydronephoresis | Hematuria | Smoking | Therapy |
|---|---|---|---|---|---|---|
| 1 | T1N- | 4 | yes | yes | neg | Cystectomy, TURBT |
| 2 | T2N- | no | yes | neg | Cystectomy, TURBT | |
| 3 | T2N- | 2.6 | no | yes | pos | Cystectomy, TURBT |
| 4 | T4N- | 0.6 | yes | yes | pos | Cystectomy, TURBT |
| 5 | T3N- | 2.5 | yes | yes | pos | Cystectomy, TURBT |
| 7 | T2N+ | yes | yes | pos | Cystectomy, TURBT | |
| 8 | T2N+ | 8 | yes | yes | pos | TURBT, Chemotherapy |
| 9 | T1N- | 3 | no | yes | neg | Cystectomy, TURBT |
| 10 | T3N+ | 4.5 | yes | yes | pos | TURBT, Neoadjuvant Chemotherapy, Palliative Radiation Therapy |
| 11 | T3N+ | 7 | yes | yes | pos | Cystectomy, TURBT |
| 12 | T2N+ | yes | yes | neg | TURBT, Chemotherapy | |
| 13 | T3N+ | 7 | yes | yes | pos | Nephroureterectomy, Adjuvant Chemotherapy |
| 14 | T3N+ | 4.5 | yes | yes | pos | TURBT, Chemotherapy |
| 15 | T2N- | 4.7 | yes | yes | neg | TURBT, Radiation therapy |