World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 2, Number 4, August 2011, pages 175-180


Sarcomatoid Urothelial Carcinoma: A Single Cancer Center Experience

Figures

Figure 1.
Figure 1. Overall survival of 14 patients with sarcomatoid bladder cancer.
Figure 2.
Figure 2. Overall survival of 14 patients with sarcomatoid bladder cancer according to stage (NMIBC: Nonmuscle invasive bladder cancer; MIBC: Muscle invasive bladder cancer).

Tables

Table 1. Characteristics of Patients of the Urinary Bladder According Histology
 
CharacteristicsUC (N = 319) (%)Sarcomatoid (N = 14) (%)P-value
CDS: Cancer Directed Surgery; UC: urothelial carcinoma
Age
  Median (Range)71 (32 - 92)63 (45 - 93)
Gender
  Male243 (76.2)12 (85.7)0.53
  Female76 (23.8)2 (14.3)
Race
  White301 (94.0)14 (100.0)0.45
  Black18 (6.0)0 (0.0)
Grade
  High Grade182 (57.1)14 (100.0)< 0.01
  Low Grade123 (38.6)0 (0.0)
  Not Specified14 (4.3)0 (0.0)
AJCC Stage
  < T2182 (57.1)2 (14.3)< 0.01
  ≥ T2135 (42.3)12 (85.7)
  TX2 (0.06)0 (0.0)
Year of Diagnosis
  2000-2005112 (35.1)8 (57.1)0.09
  2006-2011207 (64.9)6 (42.9)
CDS
  Cystectomy85 (26.6)10 (71.4)< 0.01
  TURBT alone222 (69.6)4 (28.6)
  None12 (3.8)0 (0.0)

 

Table 2. Characteristics of 14 Cases of Patients With Sarcomatoid of the Urinary Bladder
 
CaseStageTumor Size (cm)HydronephoresisHematuriaSmokingTherapy
1T1N-4yesyesnegCystectomy, TURBT
2T2N-noyesnegCystectomy, TURBT
3T2N-2.6noyesposCystectomy, TURBT
4T4N-0.6yesyesposCystectomy, TURBT
5T3N-2.5yesyesposCystectomy, TURBT
7T2N+yesyesposCystectomy, TURBT
8T2N+8yesyesposTURBT, Chemotherapy
9T1N-3noyesnegCystectomy, TURBT
10T3N+4.5yesyesposTURBT, Neoadjuvant Chemotherapy, Palliative Radiation Therapy
11T3N+7yesyesposCystectomy, TURBT
12T2N+yesyesnegTURBT, Chemotherapy
13T3N+7yesyesposNephroureterectomy, Adjuvant Chemotherapy
14T3N+4.5yesyesposTURBT, Chemotherapy
15T2N-4.7yesyesnegTURBT, Radiation therapy