World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
Journal website http://www.wjon.org |
Original Article
Volume 2, Number 4, August 2011, pages 175-180
Sarcomatoid Urothelial Carcinoma: A Single Cancer Center Experience
Figures
Tables
Characteristics | UC (N = 319) (%) | Sarcomatoid (N = 14) (%) | P-value |
---|---|---|---|
CDS: Cancer Directed Surgery; UC: urothelial carcinoma | |||
Age | |||
Median (Range) | 71 (32 - 92) | 63 (45 - 93) | |
Gender | |||
Male | 243 (76.2) | 12 (85.7) | 0.53 |
Female | 76 (23.8) | 2 (14.3) | |
Race | |||
White | 301 (94.0) | 14 (100.0) | 0.45 |
Black | 18 (6.0) | 0 (0.0) | |
Grade | |||
High Grade | 182 (57.1) | 14 (100.0) | < 0.01 |
Low Grade | 123 (38.6) | 0 (0.0) | |
Not Specified | 14 (4.3) | 0 (0.0) | |
AJCC Stage | |||
< T2 | 182 (57.1) | 2 (14.3) | < 0.01 |
≥ T2 | 135 (42.3) | 12 (85.7) | |
TX | 2 (0.06) | 0 (0.0) | |
Year of Diagnosis | |||
2000-2005 | 112 (35.1) | 8 (57.1) | 0.09 |
2006-2011 | 207 (64.9) | 6 (42.9) | |
CDS | |||
Cystectomy | 85 (26.6) | 10 (71.4) | < 0.01 |
TURBT alone | 222 (69.6) | 4 (28.6) | |
None | 12 (3.8) | 0 (0.0) |
Case | Stage | Tumor Size (cm) | Hydronephoresis | Hematuria | Smoking | Therapy |
---|---|---|---|---|---|---|
1 | T1N- | 4 | yes | yes | neg | Cystectomy, TURBT |
2 | T2N- | no | yes | neg | Cystectomy, TURBT | |
3 | T2N- | 2.6 | no | yes | pos | Cystectomy, TURBT |
4 | T4N- | 0.6 | yes | yes | pos | Cystectomy, TURBT |
5 | T3N- | 2.5 | yes | yes | pos | Cystectomy, TURBT |
7 | T2N+ | yes | yes | pos | Cystectomy, TURBT | |
8 | T2N+ | 8 | yes | yes | pos | TURBT, Chemotherapy |
9 | T1N- | 3 | no | yes | neg | Cystectomy, TURBT |
10 | T3N+ | 4.5 | yes | yes | pos | TURBT, Neoadjuvant Chemotherapy, Palliative Radiation Therapy |
11 | T3N+ | 7 | yes | yes | pos | Cystectomy, TURBT |
12 | T2N+ | yes | yes | neg | TURBT, Chemotherapy | |
13 | T3N+ | 7 | yes | yes | pos | Nephroureterectomy, Adjuvant Chemotherapy |
14 | T3N+ | 4.5 | yes | yes | pos | TURBT, Chemotherapy |
15 | T2N- | 4.7 | yes | yes | neg | TURBT, Radiation therapy |