| World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
| Journal website http://www.wjon.org |
Original Article
Volume 2, Number 5, October 2011, pages 232-237
Circulating Levels of Agouti-Related Peptide in Endometrial Cancer Survivors
Tables
| Baseline characteristics | Cases | Controls | p-value |
|---|---|---|---|
| Values given as mean ± SD, p = differences between the cases and controls analysed using Kruskal-Wallis test and Fisher’s exact test | |||
| Total number | 53 | 93 | |
| Menopausal status | |||
| Premenopausal | - | 45 (48%) | - |
| Postmenopausal | 53 (100%) | 48 (52%) | 0.008 |
| Age (yr) | 63.2 ± 10.5 | 47.1 ± 12.0 | ≤0.0001 |
| Age at diagnoses (yr) | 56.6 ± 10.4 | - | - |
| Age at menarche | 13.3 ± 1.4 | 12.9 ± 1.6 | NS |
| Age at menopause | 50 ± 5.3 | 47.6 ± 5.4 | 0.006 |
| BMI [kg.m-2] | 32.0 ± 6 | 36.1 ± 11.8 | 0.06 |
| Parity | 1.8 ± 1.1 | 1.4 ± 1 | NS |
| History of spontaneous miscarriage | 9 (17%) | 18 (19%) | NS |
| Endometrium / myometrium index (EMI) | 18 ± 9.2 / 40.7 ± 10.1 | - | - |
| Grading | 1.7 ± 0.8 | - | - |
| Length of disease-free period | 6.5 ± 4.6 | - | - |
| Self reported diabetes (%) | 34.0% | 10.8% | 0.005 |
| Plasma AgRP levels (pg/ml) | |||
| All women | 94.7 ± 29.5 | 81.5 ± 22.2 | 0.002 |
| Non-obese (BMI < 30 kg/m2) | 100.5 ± 21.12 | 88.1 ± 24.4 | 0.008 |
| Obese (BMI ≥ 30 kg/m2) | 91.5 ± 33.1 | 77.4 ± 19.8 | 0.03 |
| Parity | 0 | 1 | 2 | ≥ 3 | p |
|---|---|---|---|---|---|
| Values given as mean ± SD, p = differences between the cases and controls analysed using Kruskal-Wallis test and Fisher’s exact test | |||||
| Cases | 93.4 ± 30.4 | 93.6 ± 36.5 | 98 ± 30.4 | 89.6 ± 21 | 0.96 |
| Controls | 84.3 ± 15.1 | 80.8 ± 29.7 | 79.2 ± 21.1 | 86.2 ± 27.9 | 0.39 |