World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access |
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc |
Journal website http://www.wjon.org |
Original Article
Volume 3, Number 1, February 2012, pages 16-22
Early Experiences of Image Guided Prostate and Pelvic Nodal Irradiation With Intensity Modulated Radiation Treatment in Localized Prostate Cancer
Figure
Tables
Characteristics | Value |
---|---|
Number of patients | 12 |
Median age (years) | 64 |
Age range (years) | 50 - 74 |
Clinical stage | |
T1 | 5 |
T2 | 6 |
T3 | 1 |
T4 | 0 |
Tx | 0 |
Gleason sum | |
≤ 6 | 0 |
7 | 2 |
8 | 5 |
9 | 5 |
10 | 0 |
PSA (ng/L) | |
< 4 | 0 |
4 - 10 | 3 |
> 10, < 20 | 4 |
> 20 | 5 |
Toxicity | Number of patients |
---|---|
Acute GU Grade 1, 2 | 8/12 |
Acute GI Grade 1, 2 | 10/12 |
Late GU Grade 1, 2 | 6/12 |
Late GI Grade 1, 2 | 5/12 |
Study | RTOG 92-02 | EORTC 22863 | UK study | Norwegian study | NCI study |
---|---|---|---|---|---|
Acute GU G 1, 2 | 529/758 (70%) | 71/79 (90%) | 36/43 (84%) | 8/12 (67%) | |
Acute GU G 3, 4 | 25/758 (3%) | 7% | 1/79 (1.3%) | 1/43 (2%) | 0% |
Acute GI G 1, 2 | 666/758 (88%) | 74/79 (94%) | 34/43 (79%) | 10/12 (83%) | |
Acute GI G 3, 4 | 11/201 (5.5%) | 5% | 1/79 (1.3%) | 0% | 0% |
Late GU G 1, 2 | 12.5% (Gr 2 only) | 12.5% (Gr2 only) | 2.5% (Gr 2) | 20/43 (47%) | 6/12 (50%), 25% (Gr 2 only) |
Late GU G 3, 4 | 3.4% | 3.4% | 2.5% | 1/43 (2%) | 0% |
Late GI G 1, 2 | 9.5% (Gr 2 only) | 9.5% (Gr 2 only) | 25% | 22/43 (51%) | 5/12(42%), 8% (Gr 2 only) |
Late GI G 3, 4 | 0.3% | 0.3% | 1.3% | 0% | 0% |