World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Review

Volume 4, Number 1, February 2013, pages 8-17


Quality of Life in Patients with Advanced Cancer Using the Functional Assessment of Cancer Therapy-General Assessment Tool: A Literature Review

Figure

Figure 1.
Figure 1. The weighted mean (a) and the weighted variance (b), wi is the weight for the ith study, xi is the ith variable value, and the variance divisor d is n-1.

Tables

Table 1a. Socio-demographic and Clinical Parameters of Included Patients at Baseline
 
ParameterNo. (%)
Purpose of Study (n = 33)
  Assess Quality of Life13 (39.4%)
  Establish Reliability of External Assessment Tool10 (30.3%)
  Determine Determinants of Quality of Life7 (21.2%)
  Establish Reliability of the FACT-G3 (9.1%)
Primary Cancer (n = 33)
  Heterogeneous12 (36.4%)
  Lung7 (21.2%)
  Head and Neck4 (12.1%)
  Prostate2 (6.1%)
  Breast2 (6.1%)
  Other6 (18.2%)
Country of Study (n = 32)
  United States17 (51.5%)
  Canada3 (9.1%)
  Japan3 (9.1%)
  China3 (9.1%)
  Australia1 (3.0%)
  India1 (3.0%)
  Philippines1 (3.0%)
  South Korea1 (3.0%)
  Sweden1 (3.0%)
  Uruguay1 (3.0%)

 

Table 1b. Socio-demographic and Clinical Parameters of Included Patients at Baseline
 
ParameterNo. (%)
Gender (n = 38)
  ≤ 50% Male16 (42.1%)
  > 50% Male22 (57.9%)
Mean Age, years (n = 25)
  < 492 (8.0%)
  50 - 5912 (48.0%)
  60 - 6911 (44.0%)
Marital Status (n = 14)
  50-70% Married5 (35.7%)
  > 70% Married9 (64.3%)
High School Education (n = 10)
  ≤ 50% Completed High School4 (40.0%)
  > 50% Completed High School6 (60.0%)
College/University Education (n = 11)
  ≤ 50% Completed College/University8 (72.7%)
  > 50% Completed College/University3 (27.3%)
Admittance Status (n = 17)
  Purely Inpatients1 (5.9%)
  Purely Outpatients11 (64.7%)
  Both Inpatients and Outpatients5 (29.4%)
Median Survival (n = 11)
  ≤ Six Months4 (36.4%)
  > Six Months7 (63.6%)
Median ECOG Performance Status (n = 15)
  02 (13.3%)
  112 (80.0%)
  21 (6.7%)
Previous Chemotherapy (n = 26)
  ≤ 50%6 (23.1%)
  > 50%20 (76.9%)
Previous Radiation Therapy (n = 16)
  ≤ 50%11 (68.8%)
  > 50%5 (31.3%)
Previous Surgery (n = 14)
  ≤ 50%6 (42.9%)
  > 50%8 (57.1%)

 

Table 2. Weighted Analysis of Variance of Statistically Significant Clinical and Socio-Demographic Parameters in Relation to FACT-G Total and Subscale Scores
 
FACT-GCategoriesSum of WeightWeighted Mean (SD)P-value
* There are only 6 study arms with available information for the relationship with doctors subscale. NA: not available for calculation. SD: standard deviation.
Physical Well-being
  CountryHigh Healthcare Cost332519.93 (28.47)0.0110
Low Healthcare Cost103916.87 (43.54)
Emotional Well-being
  Admittance StatusMixed88913.30 (46.28)0.0434
Outpatient181616.59 (27.35)
  % Completing College/University≤ 30%73615.10 (28.15)0.0398
> 30%71717.66 (8.06)
Social/Family Well-being
  CountryHigh Healthcare Cost344622.06 (31.17)0.0164
Low Healthcare Cost83418.51 (35.72)
> 75%153220.73 (41.45)
FACT-G Total Scale (Excluding Relationship with Doctor Subscale)
  Admittance StatusMixed88962.60 (135.80)0.0071
Outpatient194575.58 (63.68)
  % Completing College/University≤ 30%112669.60 (103.36)0.0477
> 30%71778.49 (41.66)
Relationship with Doctor*
  CountryHigh Healthcare Cost4197.27 (1.21)0.0111
Low Healthcare Cost666.60 (NA)
  % Receiving Previous Radiation Therapy≤ 25%2227.30 (0.00)< 0.0001
> 25%477.10 (NA)