World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 5, Number 2, April 2014, pages 62-67

Outcomes of Laser Conization for Cervical Intraepithelial Neoplasia 2-3 and Microinvasive Cervical Cancer

Tables

Table 1. The Patients Included in This Study Were Summarized
 
Cases%
Patients812
Age, median (range) years37(19 - 69)
  19 - 2912215.0
  30 - 3938347.2
  40 - 4924329.9
  50 ≤647.9
Final diagnosis
  CIN 1232.8
  CIN 29111.2
  CIN 358071.4
    Ia 1718.7
    Ia 220.3
    Ib 1152.0
Adeno. (AIS/Ia)12 (10/2)1.5
Condyloma and others182.2

 

Table 2. Rates of Residual or Recurrent CIN 3 Disease After Laser Conization Are Shown
 
Conizaion + follow-upConization + hysterectomyTotal
Negative margin % (n)0.6 (3/476)5.5 (5/54)1.5 (8/530)
Positive margin % (n)9.7 (4/41)66.7 (6/9)20 (10/50)

 

Table 3. Sites of Margin Involvement and Rates of Residual or Recurrent Disease Are Shown
 
Site of margin involvementResidual/recurrent%
Ectocervix4/3511.4
Endocervix4/1233.3
Bilateral2/366.6

 

Table 4. Summary of Residual or Recurrent Lesions After Conization and Conservative Follow-Up Is Shown
 
CIN gradeMarginTime to presentation of abnormal cytologyTime to retreatmentRetreatment methodResidual lesion
TAH: total abdominal hysterectomy; PDT: photodynamic therapy; LVSI: lymph vascular space involvement; CCRT: concurrent chemo-radiation therapy.
1CIN 3positive3 M10 MATHCIN 3
2CIN 3negative5 M16 MATHAIS
3CIN 3positive13 M17 MATHCIN 3
4CIN 3positive4 M9 Mre-coneCIN 2
5CIN 3negative3 M22 MPDT→ re-coneCIN 2
6CIN 3negative3 M14 Mre-cone → 12 M ATHCIN 3
7CIN 3positive10 M28 MATH→ pTIb1 CCRTInvasive
LVSI+, pelvic LN+SCC

 

Table 5. Rates of Margin Involvement and Residual or Recurrent Disease Are Shown
 
Margin involvement (%)Residual/recurrent (%)
CIN 25.50.0
CIN 38.93.2
MIC16.413.6