World Journal of Oncology, ISSN 1920-4531 print, 1920-454X online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Oncol and Elmer Press Inc
Journal website http://www.wjon.org

Original Article

Volume 6, Number 1, February 2015, pages 292-296

Serum Protein Pattern Could Predict the Therapeutic Effect of First-Line Pemetrexed/Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma

Figure

Figure 1.
Figure 1. The 17 protein peaks with the highest area under the curve detected in the patients treated with pemetrexed/cisplatin regimen. The peaks of 3,148 m/z, 3,694 m/z, 1,250 m/z, 1,302 m/z, 4,352 m/z, 1,331 m/z, 3,183 m/z, 1,742 m/z, 4,195 m/z, 1,373 m/z, 2,769 m/z, and 8,574 m/z had higher expression in responders. The peak of 1,214 m/z, 1,020 m/z, 2,035 m/z, 2,027 m/z, and 1,002 m/z had lower expression in responders.

Table

Table 1. The Statistics of the 17 Protein Peaks Detected in the Patients Treated With Pemetrexed/Cisplatin Regimen, Mean and Standard Deviation (SD)
 
m/zP valueR (mean ± SD)NR (mean ± SD)
3,1480.000109521.81 ± 175.4355.91 ± 103.57
1,2140.0020123,926.37 ± 969.804,647.60 ± 841.31
3,6940.003286689.87 ± 363.65453.64 ± 206.30
1,2500.0040461,399.20 ± 367.011,157.82 ± 306.77
1,3020.007588838.06 ± 246.64691.54 ± 236.32
4,3520.007801344.69 ± 144.04260.71 ± 99.07
1,3310.008019645.74 ± 225.81512.14 ± 108.18
3,1830.008472408.48 ± 229.04267.72 ± 124.61
1,7420.010242489.42 ± 182.47375.91 ± 172.00
4,1950.011097387.48 ± 164.91278.95 ± 119.33
1,3730.013693855.47 ± 293.54719.61 ± 318.68
1,0200.0185933,264.40 ± 1,213.554,066.30 ± 1,458.65
2,7690.0232161,066.17 ± 709.69692.81 ± 379.49
2,0350.024369669.12 ± 384.691,026.08 ± 673.00
8,5740.0268757.66 ± 808.53427.4741 ± 361.53
2,0270.027472378.24 ± 244.43466.69 ± 214.87
1,0020.0496617,287.71 ± 1,891.808,121.41 ± 2,056.97