Postoperative Chemotherapy After Surgical Resection of Metachronous Metastases of Colorectal Cancer: A Systematic Review

Sevindzh Evdokimova, Anna Kornietskaya, Larisa Bolotina, Dmitriy Sidorov, Andrey Kaprin

Abstract


Currently, 6 months of perioperative or adjuvant chemotherapy (ACT) is a standard treatment option after radical surgical removal of metachronous metastases in patients with metastatic colorectal cancer (CRC). Data show that ACT improves relapse-free survival in such patients, although no difference in overall survival rate was observed. We perform a systematic review to evaluate the efficacy of adjuvant chemotherapy after radical resection of metachronous metastases in CRC.




World J Oncol. 2023;14(1):26-31
doi: https://doi.org/10.14740/wjon1568

Keywords


Colorectal cancer; Metachronous metastases; Adjuvant chemotherapy; Radical resection; Liver metastases

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