Multiple Myeloma Rather Than Metastatic Lung Cancer: An Unexpected Cause of Spinal Cord Compression

Chang Jun Chen, Ting Bin Yan, Ya Di Liu, Yan Wang, Xin Zhao, Yu Bin Qi, Ying Guang Wu, Kai Ning Zhang, Yan Jun Ren, Yun Yang


Spinal cord compression caused by cancer metastasis is a medical emergency that should be managed positively. Both multiple myeloma and lung cancer can lead to metastatic deposits in the spinal column to induce compression of the spinal cord. However, co-occurring multiple myeloma and lung cancer in a single patient causing spinal cord compression are rarely reported in the literature. We describe a case of a 61-year-old female with multiple myeloma and lung cancer whose radiologic characteristics of spinal cord compression mimicked those of metastatic lung cancer. Finally, the diagnosis was multiple myeloma. We showed the systematic imaging manifestations of metastatic multiple myeloma and discussed their therapeutic management.

World J Oncol. 2023;14(5):438-442


Multiple myeloma; Metastatic lung cancer; Spinal cord compression; Diagnostic challenge

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