Paraneoplastic Necrotizing Myelopathy in a Patient With Newly Diagnosed Diffuse Large B Cell Lymphoma

Abstract

Paraneoplastic neurological disorders are rare but particularly devastating forms of paraneoplastic syndromes, in part due to the fact that the entity is not usually considered as the initial differentials of a cancer patient presenting with neurological symptoms. We report a case of paraneoplastic necrotizing myelopathy associated with Diffuse Large B-cell Lymphoma in an elderly Chinese lady. After extensive investigations, the diagnosis was confirmed on spinal cord biopsy which showed extensive necrotic tissue and absence of tumour or vascular involvement.



World J Oncol. 2011;2(4):195-198
doi: https://doi.org/10.4021/wjon279w