Pemetrexed-Induced Interstitial Pneumonitis: A Case Study and Literature Review

Michael J. Waters, Shawgi Sukumaran, Chris S. Karapetis

Abstract


Pemetrexed is a new-generation antifolate drug, now widely used in patients with non-small cell lung cancer (NSCLC). We report a case of pemetrexed-induced interstitial pneumonitis, and review the literature of eight previously reported cases. As pemetrexed is now a widely used chemotherapeutic agent, it is important to be aware of rare adverse events related to its administration.




World J Oncol. 2014;5(5-6):232-236
doi: http://dx.doi.org/10.14740/wjon845w

Keywords


Chemotherapy; Interstitial pneumonitis; Pemetrexed; Lung toxicity; Non-small cell lung cancer; Treatment-related complication

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