Radiation-Induced Malignancies Making Radiotherapy a "Two-Edged Sword": A Review of Literature

Gunjesh Kumar Singh, Vikas Yadav, Pragya Singh, K. T. Bhowmik

Abstract


Radiotherapy is one of the modalities of treatment of malignancies. Radiation-induced malignancies (RIMs) are late complications of radiotherapy, seen among the survivors of both adult and pediatric cancers. Mutagenesis of normal tissues is the basis for RIMs. The aim of this review of literature was to discuss epidemiology, factors affecting and different settings in which RIM occur.




World J Oncol. 2017;8(1):1-6
doi: https://doi.org/10.14740/wjon996w


Keywords


Radiation-induced malignancies; Late side effect; Mutations

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