Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases

Ademola S. Ojo, Adedoyin Shittu, Stacy Amadife, Devon Jackson, Mica Grantham, Ahmed Ali, Ravi Sarma

Abstract


The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. We describe the case of a 45-year-old female with synchronous bilateral breast cancer with a triple-negative tumor and a contralateral HER2-positive tumor and discussed the impact of this on the approach to therapeutic management.




World J Oncol. 2023;14(3):224-229
doi: https://doi.org/10.14740/wjon1603

Keywords


Human epidermal growth factor receptor; Estrogen receptor; Progesterone receptor; Breast cancer

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