Significance of Beta Human Chorionic Gonadotropin in Predicting Disease Progression in Uterine Leiomyosarcoma

Abdulla Alzibdeh, Issa Mohamad, Maysa Al-Hussaini, Samer Salah, Abdalgani Jaradat, Ramiz Abuhijlih, Fawzi Abuhijla

Abstract


Uterine leiomyosarcoma is a high-grade sarcoma that might be associated with dismal outcome. There are no hematological markers that can be used to follow up the recurrence and/or progression of the tumor. We present a case of a 44-year-old female, who was diagnosed with uterine leiomyosarcoma. During her management course, serum beta human chorionic gonadotropin (beta-hCG) elevation was correlated with clinical and radiological disease progression on two separate occasions. This correlation should be further investigated to potentially integrate serum beta-hCG as a predictive tool for clinical behavior and treatment response.




World J Oncol. 2024;15(1):143-148
doi: https://doi.org/10.14740/wjon1748

Keywords


Uterine leiomyosarcoma; Biomarker; beta-hCG

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