Editor-in-Chief ISSN-print: 1920-4531 | ISSN-online: 1920-454X | Open Access | Bimonthly | Aims and Scope |
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- DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression
DNA damage-induced apoptosis suppressor (DDIAS) has recently been discovered to induce cancer progression, but its functions and mechanisms in glioma have not been well studied. In this study, DDIAS expression in glioma tissues was analyzed by the Gene Expression Profiling Interactive Analysis server (GEPIA) and the Gene Expression database of Normal and Tumor tissue 2 (GENT2) databases.
Read More >> - Oxygen and Iron Availability Shapes Metabolic Adaptations of Cancer Cells
The dynamic changes between glycolysis and oxidative phosphorylation (OXPHOS) for adenosine triphosphate (ATP) output, along with glucose, glutamine, and fatty acid utilization, etc., lead to the maintenance and selection of growth advantageous to tumor cell subgroups in an environment of iron starvation and hypoxia.
Read More >> - Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis
Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress.
Read More >> - Folfirinox vs. Gemcitabine + Nab-Paclitaxel as the First-Line Treatment for Pancreatic Cancer: A Systematic Review and Meta-Analysis
The efficacy and safety of Folfirinox (FFX) or gemcitabine + nab-paclitaxel (GnP) to be used as the first-line drugs for pancreatic cancer (PC) is yet to be established. We conducted an analysis of retrospective studies to assess the efficacy and safety of these two regimens by comparing their survival and safety outcomes in patients with PC.
Read More >> - Update on Radiotherapy Changes of Nasopharyngeal Carcinoma Tumor Microenvironment
The utilization of radiotherapy (RT) serves as the principal approach for managing nasopharyngeal carcinoma (NPC). Consequently, it is imperative to investigate the correlation between the radiation microenvironment and radiation resistance in NPC.
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Pigs: Large Animal Preclinical Cancer Models | Sphingosine-1-Phosphate Inhibition Increases Endoplasmic Reticulum Stress to Enhance Oxaliplatin Sensitivity in Pancreatic Cancer | |||
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Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases |
Current Issue |
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Vol. 15, No. 5, Oct 2024
Table of Contents
Review
Cryotherapy in the Treatment of Early-Stage Breast Cancer | Abstract HTML PDF |
Chelsey C. Ciambella, Kazuaki Takabe | 737-743 |
doi: https://doi.org/10.14740/wjon1909 |
Original Article
Targeting SNAI1-Mediated Colorectal Cancer Chemoresistance and Stemness by Sphingosine Kinase 2 Inhibition | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6 Suppl7 |
Harinarayanan Janakiraman, Zachary Gao, Yun Zhu, Jiangling Dong, Scott A. Becker, Alhaji Janneh, Besim Ogretmen, E. Ramsay Camp | 744-757 |
doi: https://doi.org/10.14740/wjon1890 |
On the Origin of Abdominal Venous Leiomyosarcomas: The Role of the Sex-Hormone Drainage Pathways | Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 |
Usman Tarique, David P. Cyr, Carlo Morosi, Brendan C. Dickson, Giorgio Greco, Carol J. Swallow, Dario Callegaro, Rebecca A. Gladdy, Korosh Khalili | 758-768 |
doi: https://doi.org/10.14740/wjon1884 |
Prognostic Implications of Timing of Immunotherapy in Stage IV Non-Small Cell Lung Cancer | Abstract HTML PDF Suppl1 Suppl2 |
Jorge Raul Vazquez-Urrutia, Max Greenberg, Junjia Zhu, Shinkichi Takamori, Takefumi Komiya | 769-776 |
doi: https://doi.org/10.14740/wjon1924 |
Multi-Gene Panel Testing for Hereditary Cancer Predisposition Among Patients Sixty-Five Years and Above Diagnosed With Breast Cancer | Abstract HTML PDF Suppl1 Suppl2 |
Hikmat Abdel-Razeq, Faris Tamimi, Baha Sharaf, Sarah M. Nielsen, Brandie Heald, Kathryn E. Hatchell, Edward D. Esplin, Hira Bani Hani, Khansa Al-Azzam, Mais Alkyam, Rawan Mustafa, Areej Al-Atary | 777-783 |
doi: https://doi.org/10.14740/wjon1919 |
Assessment of Five-Year Relative Survival of Patients With Endometrial Cancer: A Period Analysis | Abstract HTML PDF |
Xiao Jiao Zhao, Xin Bing, Qi Qi Lei, Yong Ran Cheng, Jun Yang, Liang You Wang, Tian Hua Chen, Tian Hui Chen | 784-791 |
doi: https://doi.org/10.14740/wjon1921 |
Analysis of Pancreatic Cancer Genetic Risk Factors in a Multi-Ethnic Population Sample | Abstract HTML PDF Suppl1 |
Abdullah Al-Qahtani, Ali Al-Ali, Bency John, Kusum Kapila, Rabeah Al-Temaimi | 792-800 |
doi: https://doi.org/10.14740/wjon1911 |
Patterns and Frequency of Pathogenic Germline Variants Among Prostate Cancer Patients Utilizing Multi-Gene Panel Genetic Testing | Abstract HTML PDF Suppl1 Suppl2 |
Ramiz Abu Hijlih, Baha Sharaf, Samer Salah, Hira Bani Hani, Sarah M. Nielsen, Brandie Heald, Edward D. Esplin, Rami Ghanem, Abdulla Alzibdeh, Tamer Al-Batsh, Yosra Al-Masri, Hikmat Abdel-Razeq | 801-808 |
doi: https://doi.org/10.14740/wjon1896 |
SNX4 Is Correlated With Immune Infiltration and Prognosis in Clear Cell Renal Cell Carcinoma | Abstract HTML PDF Suppl1 |
Yu Meng Chai, Zhong Bao Zhou, Run Ze Liu, Yuan Shan Cui, Yong Zhang | 809-824 |
doi: https://doi.org/10.14740/wjon1868 |
Simultaneous Determination of Methotrexate Concentrations in Human Plasma and Cerebrospinal Fluid Using Two-Dimensional Liquid Chromatography: Applications in Primary Central Nervous System Lymphoma | Abstract HTML PDF |
Yan Hong Wang, Qiang He, Feng Wang, Hao Jiang, Jing Shi, Ji Ma, Yu Guo Liu | 825-836 |
doi: https://doi.org/10.14740/wjon1910 |
Case Report
An Extremely Rare Case of Primary Malignant Melanoma of the Kidney | Abstract HTML PDF |
Akane Onogi, Daichi Kodama, Naoki Watanabe, Takashi Ishida, Hisao Komeda, Shuji Mikami, Takuji Tanaka | 837-843 |
doi: https://doi.org/10.14740/wjon1899 |
Secondary Hemophagocytic Lymphohistiocytosis Following Dostarlimab Treatment in a Patient With Metastatic Endometrial Cancer | Abstract HTML PDF |
Emilie Rollet, Sebastien Puigrenier, Abeer Najem, Benoit Desgrousilliers, Pierre Riviere | 844-850 |
doi: https://doi.org/10.14740/wjon1917 |
Erratum
Correction to: Empowerment-Led Guided Self-Help Intervention for Symptom Burden in Breast Cancer Women Treated With Ovarian Function Suppression: A Randomized Trial Protocol | Abstract HTML PDF |
Yuan Li, Yun Yun Chen, Su Xing Wang, Zheng Yue Dai, Jia Song Cui, Yu Fei Xing, Qing Wu, Qiong Fang | 851 |
https://doi.org/10.14740/wjon1817c |